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Job

Postdoctoral Fellow (AD/FTD Organoids)

Organization

NIH National Institute on Aging, Bethesda, MD and surrounding area

Scientific focus area

Neuroscience, Stem Cell Biology, Cell Biology, Molecular Biology and Biochemistry

The Molecular Pathology Unit of the National Institute on Aging Center for Alzheimer’s Disease and Related Dementias (CARD) is now seeking an innovative and highly-motivated postdoctoral researcher to pioneer iPSC-derived organoids in conjunction with human organotypic brain slice cultures.

About the position

Our lab's research is centered on exploring the intricacies of neuronal vulnerability and the toxicity of non-neuronal cells in TDP-43 proteinopathies, which include Alzheimer's disease and Frontotemporal Dementia. Prospective postdocs will use iPSC-derived brain cells and organoids, as well as organotypic slice cultures, to explore non-neuronal cell interactions during disease onset and progression. They will do so by leveraging a range of complementary approaches, including multi-omics (proteomics, single-cell and spatial transcriptomics, and long-read sequencing), histology, advanced microscopy, genetic engineering tool and electrophysiology. This postdoctoral researcher will also collaborate with other intramural NIH labs, extramural labs, and be supported by CARD mentors and expert groups.

Apply for this vacancy

What you'll need to apply

Interested applicants should submit a current CV or NIH Biosketch, a brief statement of their research interests and career plans, and the contact information of three professional references to Dr. Elise Marsan at the email below.

Contact name

Elise Marsan

Contact email

[email protected]

Qualifications

Applications are invited from individuals with an expertise in neurobiology, neuropathology, cell biology, molecular biology, and bioinformatics. Ideally, candidates should hold a PhD or MD/PhD. Previous experience in iPSC culture or organotypic slice culture is highly recommended, and skills in bioinformatics (scRNAseq, spatial omics analysis, R, Python) would be a plus.

Disclaimer/Fine Print

U.S. citizens and permanent residents are eligible to apply. NIH welcomes foreign nationals with the exception of individuals from this list.

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