Postdoctoral Fellow

Under the direction of Dr. Sergey Bezrukov, the Section on Molecular Transport examines the functions of beta-barrel channels, such as bacterial and mitochondrial porins, as well as various exogenous toxins. We are an interdisciplinary team of scientists combining theoretical physics, experimental biophysics, and cell biology, with a current focus on mitochondrial voltage-dependent anion channels. Our goal is to improve outcomes for mitochondria-associated diseases by using VDAC as a pharmacological target.

This prospective postdoc will study the function and regulation of ion channels on a single-molecule level using a state-of-the-art system of planar lipid membranes and nanopore methodology is available. This candidate will apply our trademark techniques, including single-channel electrophysiology and bilayer overtone analysis, in concert with biophysical and cell biology approaches to understand the role of beta-barrel channels in metabolite exchange between cells and cellular compartments.

We are seeking a highly-motivated candidate interested in ion channel biophysics and willing to learn single-channel electrophysiology and the other biophysical techniques of our lab. Candidates should have a Ph.D. in biochemistry, bioengineering, biophysics, or a related field obtained less than five years ago. Lastly, candidates should have excellent oral and written communication skills as well as publications in international peer-reviewed journals.

U.S. citizens and permanent residents are eligible to apply. NIH welcomes foreign nationals with the exception of individuals from this list.