Postdoctoral Fellow (Virginia Tech)

Our research lies at the intersection of glial biology and brain cancer, with a particular emphasis on malignant glioma, the most aggressive form of primary brain tumor. The successful candidate will investigate the role of astrocytes—one of the most abundant and functionally diverse types of glial cells—in glioma progression and their modulation of the tumor microenvironment.

This project will employ genetically engineered mouse and human glioma models, along with advanced imaging techniques, single-cell and spatial transcriptomics, and molecular biology approaches. The prospective postdoctoral fellow is expected to take part in experimental design, data analysis, as well as presentations at lab meeting, conferences, and seminars, all in efforts to prepare manuscripts for peer-reviewed publications. Additionally, the candidate will mentor research technicians and students who will also be involved in the project.

At the Ye Lab, we are committed to supporting your career development, building upon your existing expertise, and provide opportunities for you to gain new skills in a collaborative and productive research environment.

Prospective candidates must possess a Ph.D. in Biology, Neuroscience, or a related field, and their PhD must be awarded no more than two years prior to the effective date of appointment. They must also demonstrate:

• Experience with in vivo research involving mouse
• Proficiency in immunostaining and fluorescence microscopy
• Familiarity with basic molecular biology techniques (cloning, Western blotting)
• Skill with mammalian cell culture
• A track record of first-author publication(s) (preprints are acceptable)
• Preferably, hands-on experience with rodent brain surgery, primary cell culture, and a background in brain cancer, brain injury, and/or neuroscience research.