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Platelet Biology, Genomics, Cell Biology

National Heart, Lung, and Blood Institute, Framingham, MA

Position Description:

We seek talented and diverse individuals to work at the Framingham Heart Study within NHLBI. The FHS, has a wealth of genetic and OMICs data including whole genome sequence data, transcriptomes (microarray and RNA-seq), methylome, lipidome, metabolome, microbiome and proteome. Additionally, the Johnson Lab has led the collection of the largest global samples to date on platelet function and platelet reactivity, both within FHS and other cohort samples. Current analyses include focus on multi-OMICs platelet profiling, longitudinal measures, disease prediction and functional molecular studies. Relevant future research project areas for Fellows include the genetics of platelet function, bleeding disorders, pharmacogenetics of anti-platelet therapy, and the integration of multi-OMICS data, bioinformatics and machine learning to yield new discoveries.

The Population Sciences Branch (PSB) of the National Heart, Lung, and Blood Institute (NHLBI) at the National Institutes of Health invites applications for a Post-Doctoral Fellow in Dr. Andrew Johnson’s Lab. Dr. Johnson is a tenured NIH Senior Investigator with stable funding, and a research lab based at the historic Framingham Heart Study (FHS). The FHS was started in 1948 with a focus on unlocking the risk factors behind cardiovascular disease. The Johnson Lab is highly focused on understanding platelets and their role in both bleeding and cardiovascular disease, and how we may improve anti-platelet therapeutics. Trainees in the Johnson Lab have gone onto successful careers in industry and academia, and the Lab has >39,000 citations to its work with a current h-index >100.

We collaborate widely with several Domestic and International Consortia in the area of Hematology (platelet count), Hemostasis (coagulation, hemostatic and fibrinolytic factors), and cardiovascular risk (MI, stroke, VTE). We are co-leading genetic projects on platelet counts in ~1.2 million individuals in sample size to generate new target genes controlling platelet biogenesis and decay. We also have a molecular lab focused on translating our population discoveries into functional cellular experiments at the main NIH campus.

The successful candidate will be offered a competitive salary commensurate with experience and qualifications. The initial appointment will be for a minimum of 2 years, with appointment renewals in 1-year increments. The post-doc must be a US citizen, resident alien, or nonresident alien who obtains a valid employment visa.


Applicants must have an M.D. and/or Ph.D. and research experience in 1 or more of the following: Epidemiology, Hematology, Platelet Biology, Statistical Genetics, Molecular/Cellular/ Biology, Genomics, Pharmacogenomics, and/or Bioinformatics. A proven track record of prior publications is expected.

To Apply:

Applicants should submit a cover letter highlighting key qualifications and research interests, and curriculum vitae with complete bibliography to:

Andrew D. Johnson at

The NIH is dedicated to building a community in its training and employment programs and encourages the application and nomination of qualified women, minorities, and individuals with disabilities.