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DNA Topology and Chromatin Structure

National Cancer Institute, Bethesda, MD and surrounding area

Position Description:

A postdoctoral fellow position is available in the laboratory of Dr. Chongyi Chen at the National Cancer Institute (NCI), National Institutes of Health (NIH). The potential projects are to investigate the dynamics and regulation of DNA topology upon mitotic chromosome condensation, and to investigate the role of DNA topology in gene expression regulation in human cells. The Chen lab study chromatin structure, DNA topology, and gene expression regulation in human cells, by various genomic technologies and single-cell sequencing assays newly invented in the lab. For more information about the lab and the PI, please visit:


We are looking for candidates with strong backgrounds in molecular cell biology, genomics, bioinformatics, or related fields who are passionate and self-motivated in research. Candidates with prior experience in chromatin biology or omics data analysis are especially encouraged to apply.

To Apply:

Interested applicants should send a CV including a publication list and the contact information of references to

This position is subject to a background investigation. The NIH is dedicated to building a diverse community in its training and employment programs.