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Lysosomes in Health and Disease

National Heart, Lung, and Blood Institute, Bethesda, MD and surrounding area

Position Description:

A postdoctoral position is available in the Cell and Developmental Biology Center (Rosa Puertollano, PI) at the National Heart, Lung and Blood Institute. The successful candidate would join a multi-disciplinary and highly interactive team of researchers with diverse backgrounds and expertise in a collaborative scientific environment. We are interested in understanding the mechanisms that regulate traffic of lipids and proteins in the secretory and endocytic pathways, and how defects in sorting lead to human diseases. Current projects include the study of endo/lysosomal TRP channels, the characterization of the role of mTOR and TFEB in lysosomal biogenesis and nutrient sensing, and the elucidation of new approaches for the treatment of lysosomal storage disorders. We use a wide range of cell biology techniques (molecular biology, protein biochemistry, confocal microscopy) as well as in vivo animal models (mouse and zebrafish). For more information, please visit:


Applicants must have a Ph.D. or equivalent with less than five years of postdoctoral experience, an ability for independent research, a strong interest in interdisciplinary approaches and collaborations, and relevant publications in peer review journals. Demonstrated strong background in cellular and molecular biology, and/or experience with in vivo animal models (rodents and zebrafish) is preferred. Salary is commensurate with research experience and accomplishments

To Apply:

Applicants should send their curriculum vitae, a brief statement of research interests, and the names and contact information of three references to:

Rosa Puertollano Ph.D.
Senior Investigator–Laboratory of Cell Biology
Building 50, Room 3537
50 South Drive, Bethesda, MD 20892-1454, USA

The NIH is dedicated to building a community in its training and employment programs and encourages the application and nomination of qualified women, minorities, and individuals with disabilities.